Bioactive Small Molecules
A vast array of small, non-peptide, organic compounds that are biologically active. Products include receptor antagonists, molecular probes, metabolites, GPCR ligands, neurotransmitters, ion channel modulators, and signaling activators and inhibitors.
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Tocris Bioscience™ CHPG
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CAS: 170846-74-9 Molecular Formula: C8H8ClNO3
| CAS | 170846-74-9 |
|---|---|
| Molecular Formula | C8H8ClNO3 |
Tocris Bioscience™ RWJ 67657
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CAS: 215303-72-3 Molecular Formula: C27H24FN3O
| CAS | 215303-72-3 |
|---|---|
| Molecular Formula | C27H24FN3O |
Tocris Bioscience™ PMPA (NAALADase inhibitor)
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CAS: 173039-10-6 Molecular Formula: C6H11O7P
| CAS | 173039-10-6 |
|---|---|
| Molecular Formula | C6H11O7P |
Tocris Bioscience™ DAPT
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CAS: 208255-80-5 Molecular Formula: C23H26F2N2O4
| CAS | 208255-80-5 |
|---|---|
| Molecular Formula | C23H26F2N2O4 |
Tocris Bioscience™ JTV 519 fumarate
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Ryanodine receptor (RyR) inhibitor
| Product Type | JTV 519 fumarate |
|---|---|
| Molecular Weight (g/mol) | M.W. (Observed): 540.67 |
| Purity | 98% |
| Recommended Storage | Store at +4°C |
Tocris Bioscience™ PF 05180999
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Potent and selective PDE2A inhibitor
| CAS | 1394033-54-5 |
|---|---|
| Chemical Name or Material | 4-(1-Azetidinyl)-7-methyl-5-[1-methyl-5-[5-(trifluoromethyl)-2-pyridinyl]-1H-pyrazol-4-yl]-imidazo[5,1-f][1,2,4]triazine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C19H17F3N8 |
| Formula Weight | Observed MW: 414.39 |
| Assay Percent Range | >98% |
Tocris Bioscience™ TRPV3 74a
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Selective TRPV3 antagonist; brain penetrant
Tocris Bioscience™ Amphotericin B
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Forms monovalent ion channels in lipid bilyers
Tocris Bioscience™ Entecavir
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Potent and selective hepatitis B virus inhibitor
| CAS | 142217-69-4 |
|---|---|
| Product Type | Inhibitor |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C12H15N5O3 |
| Formula Weight | 277.28 |
Tocris Bioscience™ Thalidomide 4'-ether-PEG2-alkyne
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Thalidomide-PEG2-alkyne
Tocris Bioscience™ FK 228
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CAS: 128517-07-7 Molecular Formula: C24H36N4O6S2
| CAS | 128517-07-7 |
|---|---|
| Molecular Formula | C24H36N4O6S2 |
Tocris Bioscience™ SB 399885 hydrochloride
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CAS: 402713-81-9 Molecular Formula: C18H22Cl3N3O4S
| CAS | 402713-81-9 |
|---|---|
| Molecular Formula | C18H22Cl3N3O4S |
Tocris Bioscience™ DCG IV
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Highly potent group II mGlu agonist; also NMDA agonist
| Target | Group II mGluR Agonists |
|---|---|
| CAS | 147782-19-2 |
| Solubility | Soluble to 100mM in water |
| Purity | 98% |
| Chemical Name or Material | (2 S,2 'R,3 'R)-2-(2 ',3 '-Dicarboxycyclopropyl)glycine |
| Recommended Storage | Store at -20°C |
| Molecular Formula | C7H9NO6 |
| Formula Weight | Observed MW: 203.15 |
| Assay Percent Range | >98% |
Tocris Bioscience™ 5,7-Dichlorokynurenic acid sodium salt
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Sodium salt of 5,7-Dichlorokynurenic acid (Cat. No. 0286). Potent NMDA antagonist, acts at glycine site
| Inhibitors | 5,7-Dichlorokynurenic acid sodium salt |
|---|---|
| Product Type | 5,7-Dichlorokynurenic acid sodium salt |
| Molecular Weight (g/mol) | 280.04 |
| Purity | >98% |
Tocris Bioscience™ PHA 767491 hydrochloride
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CAS: 942425-68-5 Molecular Formula: C12H12ClN3O
| CAS | 942425-68-5 |
|---|---|
| Molecular Formula | C12H12ClN3O |